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The plant cell wall biotechnology group studies the structure and function of plant cell wall components in hopes of exploiting this knowledge for the production of valuable biological products
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Participating Faculty
- Jared L. DeForest - Env. & Plant Biol; Mechanisms of plant cell wall degradation
- Ahmed Faik - Env. & Plant Biol; Plant cell wall biochemistry
- Allan Showalter - Env. & Plant Biol; Molecular biology and biochemistry of plant cell wall proteins
- Sarah Wyatt - Env. & Plant Biol; Plant Development, Molecular Biology
- Marcia J. Kieliszewski - Dept. of Chem. and Biochem.; Structural analysis of plant cell wall proteins
Current and Past Projects
* Arabinogalactan-proteins: structure, expression, and function (Showalter)
* Characterization and cloning of the gps mutants of Arabidopsis (Wyatt)
* Crystallization of hydroxyproline-rich glycoproteins for structural determination by X-ray diffraction and three dimensional molecular modeling (Kieliszewski)
* Effects of light on lignification and secondary cell wall production in Arabidopsis (Wyatt)
* Gene discovery during induction of reaction wood using Arabidopsis as a model (Wyatt)
* Glycosylation site mapping of hydroxyproline-rich glycoproteins (Kieliszewski)
* Isolation and characterization of tomato arabinogalactan-protein and extensin genes (Showalter)
* Molecular interactions and cross-linking of hydroxyproline-rich glycoproteins (Kieliszewski)
* Molecular interactions and functions of LeAGP-1, a modular plasma membrane arabinogalactan-protein (Showalter and Kieliszewski)
* Production and characterization of arabinogalactan-protein mutants in Arabidopsis and tomato using antisense and RNAi technology (Showalter)
* Programmed cell death in plants and the role of arabinogalactan-proteins in this process (Showalter)
* Structure and function of a novel, modular arabinogalactan-protein from tomato (Showalter and Kieliszewski)
* Synthetic genes for de novo glycoprotein design and the elucidation of hydroxyproline-O-glycosylation codes (Kieliszewski)
External Funding Sources
- American Society for Gravitational and Space Biology
- National Science Foundation
- Ohio Board of Regents
- Ohio Plant Biotechnology Consortium
- U.S. Department of Agriculture
Useful Links
Bioethics
Case Studies
http://ublib.buffalo.edu/libraries/projects/cases/ubcase.htm
National
Science Foundation
http://www.nsf.gov/start.htm
Pedro's BioMolecular Research Tools http://www.public.iastate.edu/~pedro/research_tools.html
Pub
Med
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi
Stanford
Microarray Database
http://genome-www5.stanford.edu/cgi-bin/SMD/login.pl
Tomato
Anatomy
http://www-plb.ucdavis.edu/courses/plb105/Students/Tomato/Tomhome.html
Transgenic
Tomato
http://www.nalusda.gov/pgdic/cris-icar/tomato.html
The
Institute for Genomic Research
http://www.ebi.ac.uk/blast2/